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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48561f4b3a94fd12cf7862a37d35e4484deda7729d112d76b48a5d105f8624ac' 
  AND token = '1vIzSYAU9ytBoadZslF0v4KHSYmZxGA7LiltXtMjRkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}