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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7295fb34bc4a38efa67b7b2489f9bd91fac03fd442f745623622e3a3d0b6cdc' 
  AND token = 'iDIlrRkWwR4qoSZgBeMQVj4TTAIjHcUmkanTRodAH9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}