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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e9b4ea79bf45fba53f8e42e2383c1e68b34064eee6b6f0b57478b3c60e4c15' 
  AND token = 'MyWu/EFe/JEudRDE+mF93QEOSNJotHYs3LCj/8r8yYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}