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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701c1f43ac03292a3b1b5b27df8110ed41b8992a8494741fb157d3a56cc105e8' 
  AND token = 'uBsVkPzUvrD7Kbuvl7kuoXtJsBmtrWUEGyuy8pJRw3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}