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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81167270e60321dc4e34bccbdc36cb375108a9716eae01569c5fb7d10565dab' 
  AND token = 'nQte9VfiBmsXwLroxEn0w++ESBXzW8n0qtNQ4pUwSlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}