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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c44d2bf437d84f0e4819e19cb09be6f89150c4dfac1b7b18111dd0a795f5a7c' 
  AND token = 'pxDuWviaamEJ0GCQTnuUawj0lcWRRs2V55xnY2mF8c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}