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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd8e75b00f180f9b8ced686eed4c53a66155166bb1d086ea2724f61db635e66' 
  AND token = 'rCNJ1PBbPH8p/wkL4ut0gyKZ1xsxSZmvDXq9yFETLeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}