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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f485ea79d953c32c703e3c66192269e2e88a7aacd132c40c81e97ccfb8eccc0' 
  AND token = 'ttEAPeRaOaq2m8RdiHN1fo+iVz3XRh6R6TzE2RsvMHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}