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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05c64d73393f537023e57e1b7b3a34eba7b32e3734007794c77cb4a4a532e5c' 
  AND token = '8UFEGCMsVgBO6PPGiEioXimEy6gB3lKsyqlj6OU4rho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}