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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7d3f789a020d0c422c92d8c65d29d85fd5a08b2adaf16acd529c71d6a775d9b' 
  AND token = 'PtSI/MhJFvwCL2//NlhqlaFPv/07EPLBEDeMkNP9ZYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}