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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd35437e01554d38a13470e7b5fe28224b8797284d0607395f03f5dc9f04cdf53' 
  AND token = 'ojZsk4hAAxi9WaRRiFdl2G1XcxUiD2rRkXYghCHHSVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}