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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee3057651987fe2385f2634680dc1d55b10164031b1feaaa2d356a3ec70da770' 
  AND token = 'Owv456Dt56vkmLxY6++HXHglAudM+qhwSP/0vUViKUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}