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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82ff080a7847d9ae32f77fb7f9ee74cc286e61d649e85ee45fff004ddff79474' 
  AND token = 'lOIs7d/IE64XpmqIixTKZJxwVAb/thrdKnkX0Se3iBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}