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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88428c1f2274540d2d2b62db4574cc9bff3638ef354a2bbcf6f60a44a709cee4' 
  AND token = '4INAQwcNj5IEpO1y70DKlATq/KMDP1aMp/3wzx0zEpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}