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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d73f7ddca38f5da56b1850b2282a96d33d0b384bfebd6ccd1baa9e68d2b8dd5' 
  AND token = 'rUuV/AkW8RN3PDKjI2rDS0OgXFzc8EFyZGWKEbBm2Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}