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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f45ec6d73aa11e0825d6eb83596a628cc419a06bf5cdf824161fb545465de64' 
  AND token = 'tHEDrTAzioh4BL87zsBUqecf1U7juuGPuNZI7YH2ZaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}