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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49717d3ef20d705e7436645e9a83881191e2bd2d6d5b257e003cc4fb9164899a' 
  AND token = 'jFiX6t2YjVsDnQHNE+6J0zTuItzFJWEaweuhpybOo0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}