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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2285eeae80d34bf158f06fddba784a5641a9db173ff5646ff7e7b936b4b555bb' 
  AND token = 'PQacLvDBqfNxNPD/9lRD6AhjPWuxdMmAWP20U3l/vpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}