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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241cdf0de2da27d1394103d4dc8db6d75b62819f561e481966ecc0642e528db1' 
  AND token = 'F/8K29CiXajK2aEKGvlNmwqLU1GKmXAKlteaiC1ejsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}