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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d14bd74266b4980a69b455261e396309b70acc91c8fca0ab9605e644725f14d' 
  AND token = '/Mmalk1Tc57aeD9rAG+Nxu3j9a1VG+Shenp+H8WcZpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}