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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4000d36e746a3570f6bc960173d48be086c1d524069e52681c827c76bfe22c' 
  AND token = 'koU7/BnOMyCIvq0CX6ITyzoyiEEohckVU++2eKVa0TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}