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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41618d860e9f9565cdf3555e20e1860b9dfbe57e06808bf923b24f1fb258dfa6' 
  AND token = 'TrVLx0LbrzCFMcIyFo51CestqBpRI/ibqqHVUGPrC1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}