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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53cf7ea6ad485b1a66f055f14793d12076d0ebd917803e50705d596a53f0369c' 
  AND token = 'Zn/vss2Yv/EfQxdhWzPOSOaiHEAxwJe87ksr6IZGF4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}