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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '791494cca6b1c06c3ee175a8ae972c6a0fc00c56ce2c967056eade777e401e70' 
  AND token = 'MsK9I8xKUCHSa66v88w9ZZ/pRa4kW7MFTcm+tKkt6es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}