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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c768b5009619d37c637118a9337ef16587defeeccd7ad1dcae23f2fedd3c3bd' 
  AND token = 'rD0iHrfEj8a6WK/s9xSZZtoBLEYi1QHZkV4P0ylmi1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}