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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d046306aef224177dfb877446552d48a019a950dcf78b92cd3ef49ff93a2ec5' 
  AND token = 'G75sTeKnkMLX/HND1w81wtmhnPRtkjCU7u3A/Nzo+a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}