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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9d515214eccda63576af4880c05a3048e394ef524012315ef73430e4dbc3b1' 
  AND token = 'bxI2g2ah0FrJg8xl12+J7zw4VM7v5UvJWfM1LH+bqtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}