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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3443384649fb7d7c83e1241b0e892ecb1ffeafc62bc8dbec1e323db1eec886a6' 
  AND token = 'zjHMMefmkQQy7eJ6+GD0VwoR6+pPUAizTC2Rn5tKYoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}