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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6d5457aa34ac22a29ee25e33030f309f71e3434167d2240b27b8ad99ff8655' 
  AND token = 'uPouHOIW0ylx9Y4gFI861yWVZmuixH277yh8gdfUE4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}