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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb217b53e3dc26bc6f68f6146d1841f6fd50ddaf71196177bc8540f343246d48' 
  AND token = 'Ip7PsnyP8Kcdjk8jQQUmQLISUf+QrQcL1lhydfbqb7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}