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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b518caf691a087a5e0d85f95f37544d8b99f629f20b32d947a1e7e0b321c75' 
  AND token = 'HathCKlJ18h8TPdGKqUHaTBS5GNNyl5LYo9w8QyUMCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}