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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dbdcb3e45a3dc43a204d2c22fcdee25a0b183a77a6e8106ef162925b5815998' 
  AND token = 'VxaP+RXQlVctgYErtF/WdQoz3lwUgGgWziy77+G+3G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}