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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50e3c341fd99de196a1fb3bde3e1754742e2b0b8d05592c0caffcfb994cd5b7' 
  AND token = 'QfLepp8LMnUeb+IGxvyburgCDvD8ZhrxzPVBGVvYEOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}