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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '635f566f3657def620c514f305eb89fb0b2ec33906821bb748304f08ad644649' 
  AND token = 'LdYj1YV1ZrjKpaVS6+md72hPvp9jdn96Hb8KSNNywN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}