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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8182b91a47d041c866488866a8c6fe172957dedf22d2bb585f2f44fb568d3b7' 
  AND token = 'QMcELA/Oy8/3jS3kNt1L2UV4IuoW7SXt34StJ5z3AIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}