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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01eed5950011264e4c907b0162ea5badb4676736cf9ac414f05bae1811db27a4' 
  AND token = 'E3sH++SNx65kYwPOHeYntrU7biDah6/CglArd2h3kqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}