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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b848ef3a0187aabcb3e43007605baef00203c631c4aa5b51d7311d92adb35b3e' 
  AND token = '0e2BhxtKyYAd7qGsJtJ5+T7ZeG3GxN9mdbABGMF8EGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}