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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481bafa38453389abef5093fae59b26f103d76e6f48f562e5e6c28bac475bca2' 
  AND token = '2AzL607qj+5mq5s6vs4x2zqRQsqvhfcy6PVxXTw1ATY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}