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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399b06bfb7a0e5021307cb8d4c4ec7d89f3018581958e280ba9a5c2f35cf2523' 
  AND token = 'mz59hnxa9nBl/wnfE9Y3vHMGYQsEeIOXFn9K8yBWCko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}