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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edb8f27c35f5fb8cd3f41aca4cef9c5860dd124b52604d1f1fd9a2cc48900bc6' 
  AND token = 'RGut2XkA8ijmpu/0GNaCZtUD4CCqSbmoOjETXUoRc2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}