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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a4d69c0d0364a69679fba47c0edca27e5f4155a659fd20630f5939a889c019' 
  AND token = 'efUVqz0iL8tcDnn1jGu5Jjtd9z2XZ5rVLe1OM8X2jFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}