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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aef1cfca27831bbd2df177007109707acb554bfa460d0a5b8c7b5461290e5b9' 
  AND token = '39kS8Wg9+pZS5rxOJPBU8IcStSHUZnigXB6CJvFk7VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}