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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a73ad523c58aa239d8047697b6f05edfc89b640db6cdb1c88fcf290cabc6a3f' 
  AND token = 'w7jlOKfvKP6clfSOYZrhs7DTyzhDhZUbh3cSkkx6QMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}