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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a333e68cdc4d23abd320a6b1206604f17cf42a3bfb771212acd2e5921d796a8' 
  AND token = 'T8x+KIXNY4DwbiBJQ+EB4SaL7so/t4NHsy20lrTJ0rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}