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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5588fdd53bd342044c5f40c86568b549f3c10c46ec500ad9b79ca9ba313fbec' 
  AND token = 'BMadftSt6m61ni0J9mWsHX2t/kEZhe6iWE6Qggc7C60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}