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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2683649a956006f9434031c537a0db332956d7b86e975a2df983c77cdc4e8aec' 
  AND token = '3zXwz1dc1NIuq90dWhrs2UID6xkoBewVln5hwbhAaMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}