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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b1c8b6f8a3ff70c9a9651f90f55196a4f97bd9da29daa7022a0379ef3dace2' 
  AND token = 'Ls6uoPqHLfV14AxgZg9AZ2AcTRF26MHoNIgQ0CWbyjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}