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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f879494f199e66ece1aa9390d79ca59c79c5939648b6556abb9421a3f6a106' 
  AND token = 't0wPQW4zXsJYwDMA7dRVjix/jRkVM3BUcbL52cR5a94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}