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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4481231d1523c70d1914c3da1f9bba22959025e42b9170b620f4d6149950ac' 
  AND token = 'S8enrM74R+CZBQQv8dboOIOsoF2gx5OPLN7D+2hYf8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}