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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331f56e876a413e5c276ca131c42d1d73716bb854bd64d9cd80aabd47572aa33' 
  AND token = 'zEZ2XQDefX9942Pud8//xN8UFB5tDCjqOcENpoPATh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}